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Lispro
  • Insulin Preparation
  • Type: Rapid Acting
  • Peak: at 15 mins
  • Duration: 3-4 hours
Regular Insulin
  • Insulin Preparation
  • Type: Rapid Acting
  • Peak: at 30 mins - 3 hours
  • Duration: 5-8 hours
NPH (isophane)
  • Insulin Preparation
  • Type: Intermediate Acting
  • Peak: at 8-12 hours
  • Duration: 18-24 hours
Lente
  • Insulin Preparation
  • Type: Intermediate Acting
  • Peak: at 8-12 hours
  • Duration: 18-24 hours
Ultralente
  • Insulin Preparation
  • Type: Slow Acting
  • Peak: at 8-16 hours
  • Duration: 20-36 hours
Glargine (Lantus)
  • Insulin Preparation
  • Type: Very Slow Acting
  • Peak: No Peak
  • Duration: 18-24 hours
Visual Aid
Sulfonylurease
  • Type II Diabetes Drug
  • Mechanism of Action: Stimulates insulin secretion (receptor mediated)
  • Preferred Patient N/A
  • Side Effects: Hypoglycemia
Metformin
  • Type II Diabetes Drug
  • Mechanism of Action: 1)Decrease Hepatic glucose production 2) Increase enry into cells (mechanism unknown) ( same end results as thiazolidine-diones - "insulin sensitizer" but dif mechanism so dif pts and dif side effects)
  • Preferred Patient Type: for Overweight or Dyslipidemic patients
  • Side Effects: Lacticacidosis in patients with renal disease
Acarbose
  • Type II Diabetes Drug
  • Mechanism of Action: 1) Inhibits intestinal alpha-glucosidase and decrease absorption of carbohydrates 2) Decreases postprandial hyperglycemia
  • Preferred Patient Type: for overweight or dyslipidemic patients
  • Side Effects: Gastrointestinal
Thiazolidine-diones
  • Type II Diabetes Drug
  • Mechanism of Action: "Insulin sensitizer" Acts directly on insulin regulated genes - bypasses insulin receptor (PPAR) 1) Increases glucose entry into cells 2) decreases hepatic glucose production (same end result as metformin but dif mechanism so dif pts and dif side effects)
  • Preferred Patient Type: Insulin resistance
  • Side Effects: Liver dysfunction (expensive)
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