Cloned from: USMLE Pharmacology



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-afil
ED
-ane
inhalational general anesthetic
-azepam
benzodiazepine

CNS depressant

change receptor so GABA binds w/ higher affinity

Application: anticonvulsant
-azine
phenothiazine
(neuroleptic, antiemetic)
-azole
antifungal
-barbital
barbiturate
-caine
local anesthetic
-cillin
penicillin
-cycline
antibiotic

protein synthesis inhibition
-etine
SSRI
-ipramine
TCA
-navir
protease inhibitor
-olol
beta-antagonist
-oxin
cardiac glycoside

(inotropic agent)
-phylline
methylxanthine
-pril
ACE inhibitor
-terol
beta2 agonist
-tidine
H2 antagonist
-triptan
5-HT 1B/1D agonists
(migraine)
-triptyline
TCA
-tropin
pituitary hormone
-zolam
benzodiazepine
-zosin
alpha1 antagonist
Toxin:

acetaminophen
N-acetylcysteine
Toxin:

salicylates
NaHCO3 (alkalinize urine)

dialysis
Toxin:

amphetamines (basic)
NH4Cl (acidify urine)
Toxin:

anticholinesterases
organophosphates
atropine, pralidoxime
Toxin:

antimuscarinic
anticholinergic
physostigmine salicylate
Toxin:

beta blockers
Tx:

glucagon
Toxin:

Digitalis
Stop dig, normalize K+, lidocaine, anti-dig, Fab fragments, Mg2+
Toxin:

Iron
deferoxamine
Toxin:

Lead
Ca EDTA
dimercaprol
succimer
penicillamine
Toxin:

mercury
arsenic
gold
dimercaprol (BAL)
succimer
Toxin:

Cu, As, Au (gold)
penicillamine
Toxin:

cyanide
nitrite
hydroxocobalamin
thiosulfate
Toxin:

Met-Hb
methylene blue
Vitamin C
Toxin:

carbon monoxide
100% O2
Hyperbaric O2
Toxin:

methanol
ethylene glycol (anti-freeze)
ethanol
dialysis
fomepizole
Toxin:

opioids
naloxone/naltrexone
Toxin:

Benzodiazepines
flumazenil
Toxin:

TCAs
NaHCO3 (serum alkalinization)
Toxin:

heparin
protamine
Toxin:

warfarin
vitamin K
fresh frozen plasma
Toxin:

tPA, streptokinase
aminocaproic acid
Toxin:

theophylline
beta blocker
bethanechol
direct cholinometric agonist

post-op & neurogenic ileus & urinary retention

activate bowel & bladder SM; resists AChE

"Beth Anne calls" bc need to use the restroom after taking bethanechol.
carbachol
Direct cholinomimetic agents

Glaucoma, pupillary contraction, and release of intraocular pressure
pilocarpine
direct ACh agonist

potent stimulator of sweat, tears, saliva

contracts ciliary muscle (open angle), pupillary sphincter (narrow angle); resistant to AChE

"pile on sweat, tears, saliva"
methacholine
direct ACh agonist

challenge test for asthma diagnosis

stimulates M3 receptor in airway when inhaled
neostigmine
indirect agonist (anti-AChE)

post-op & neurogenic ileus & urinary retention, myasthenias gravis, reverse neuromuscular junction blockade (post-op)

incr ACh, no CNS
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