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A unit of packed RBC's is split using the open system. One of the half units is used. What may be done with the other half unit if maintained at 4C?
Must be issued within 24 hours.
When performing an Rh typing, the results obtained for an Rh-negative individual are:
Anti-D: negative.
Rh control: negative.
A patient is admitted to the hospital and requires two units of blood. On crossmatching, one donor which is type A R2R2 shows 3+ agglutination with the patient at 37C. The second unit, a type A R1r is compatible. What is the most likely antibody present in the patient's serum?
Twenty minutes into a second transfusion of packed RBC's, the patient experiences chills, fever, and a temperature increase of 2C. Post reaction samples of urine and blood show no evidence of free hemoglobin or blood. Repeat testing of serum from both pre and post transfusion blood samples were negative. This reaction should be classified as:
Febrile nonhemolytic transfusion reaction.
Mr. Harris has a hemoglobin of 7g/dL and his physician would like to raise it to 10 g/dL before surgery. How many units of packed cells should be ordered?
What is the minimum allowable donor weight?
110 lbs.
In which blood group do you find the greatest concentration of H?
Type O.
Which group of antigens would always be considered as clinically significant?
D, E, Fya, S, A, B, K.
While an elderly, anemic patient is receiving a transfusion of RBC's, he experiences difficulty in breathing, cyanosis, coughing, and frothy sputum. He has a history of cardiac failure. What is happening to him?
He is suffering from an increase in his circulating blood volume. He should have been transfused slowly to increase his Hb without increasing his blood volume.
A blood bank storage refrigerator must operate within what temperature range?
1 to 6C.
A secretor is defined as an individual who:
Produces soluble ABH group substances in secretions.
What result might you see in an acquired B?
Anti-A: positive.
Anti-B: positive.
A1 cells: negative.
B cells: positive.
Rh immunization most often occurs following:
Transfusion of RBC's.
A unit of RBC's was released to the floor for a patient. Twelve hours lated the unit is returned to the blood bank. The unit appears to be hemolyzed. The most appropriate action is to:
Discard the unit.
The Weiner notation rr" translates to Fisher-Race as:
Frozen RBC's are good for:
10 years at -65C.
A patient with an acute HTR is most commonly caused by:
ABO incompatibilities.
When a patient receiving a platelet transfusion experiences purpura, the most likely cause is:
Anti-platelet antibody.
In the weak D testing procedure, the AHG serves what purpose?
Bridging antibody molecules attached to RBC.
The blood bank obtained the following results on the blood for a surgical patient needing 4 units of blood.
Anti-A:  4+        Anti-B:  0
A1 cells:  2+       B cells:  0
Anti-D:  4+        Control: 0
Auto control: 0
What is the next step?
Test the patient's serum with A2 cells and the RBC with anti-A1 lectin.
You have a patient with a n antibody indentified as anti-K. This patient's cells are K positive. What type of antibody is this.
Antibodies in the Rh system are:
Usually IgG.
How many doses of RhIg are administered for a fetal cell bleed of 25 mL?
None are required for 30 mL or less.
The Weiner notation R2R2 translates to Fisher-Race as:
Which characteristics are true of all THREE of the following antibodies: anti-Fya, anti-K, and anti-Jka?
Detected at AHG, may cause HDN, and transfusion reactions.
A unit of fresh frozen plasma is thawed at the request of a physician. The physician then decides NOT to transfuse the plasma. Thirty-six hours later the physician wants to transfuse the previously thawed unit to the same patient. What action should be taken?
Thaw another unit of fresh frozen plasma for the patient.
When an intrauterine transfusion is required, which is correct?
A unit must be less than 7 days old.
A donor unit contains a warm-reacting antibody. According to AABB what should be done with this unit?
The RBC's can be used but the plasma must be discarded.
If a crossmatch is ordered on a patient with an alloantibody, which procedure may be employed?
Extended panel.
Enzymes enhance the reaction of which antibody?
Antibodies to D antigen are usually produced:
As a result of immunization by a red cell.
A positive direct antiglobulin test indicates:
In vivo cell sensitization.
Auto antibodies are:
Antibodies directed against an individuals own red cells.
A father is R1r and a mother is rr. What percentage of their offsprings will be Rh positive?
A patient's serum reacts with 10 out of 10 donor units in an extended crossmatch at AHG. A two-cell screen of the patients serum is also positive but the autocontrol is negative. Which is the MOST likely explanation for these results?
The presence of an antibody against a high incidence antigen.
When a patient's samples shows a discrepancy between the forward and reverse grouping with missing or weak reactions, what can be done to enhance these reactions?
Incubate 15-30 minutes at room temp or 4C.
The weak D antigen is:
A weak variant of D.
Antibody titers are used to:
Predict the severity of HDN.
This is known as the failure or false negative result in an agglutination reaction due to the excess of antibody to antigen.
Coombs' control cells should not show agglutination with:
An antibody against which Rh antigen is associated with warm-autoimmune hemolytic anemia?
Which procedure would help to distinguish between an anti-e and anti-Fya in a patient with both antibodies?
Run an enzyme panel.
Bacterial contamination of blood products due to a bacteria that grows well at 1-6C is most likely due to:
Yersinia enterocolitica.
Why should a patient's cells used in a DAT be washed before adding AHG?
To prevent neutralization of AHG by free Ig in the serum.
A hospital blood bank receives units from the regional blood center. In addition to confirming the ABO grouping, which of the following confirmatory tests must the blood bank perform on each unit?
Rh on all D negative units.
In comparing the plasma of a pre and post transfusion reaction specimen, which would NOT indicate probably HTR?
According to AABB standards, the lab must retest the Rh of what type units?
Rh negative.
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