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PRH


Prolactin Releasing Hormone

Source: Hypothalamus
Target: Lactotropes
Action: Stimulate PRL synthesis and release
PRL is Protlactin
Dopamine
Source: Hypothalmus Target: Lactotropes
Action: Inhibit PRL synthesis and release

TRH


Thyrotropin Releasing Hormone
Source: Hypothalmus
Target: Thyrotropes
Action: Stimulate TSH synthesis and release
CRH


Corticotropin
Source: Hypothalmus
Target: Corticotropes
Action: Stimulate ACTH synthesis and release
GHRH


Growth Hormone
Source: Hypothalamus
Target: Somatotropes
Action: Stimulate GH synthesis and release
GHIH
Source: Hypothalamus
Target: Somatotropes
Action: Inhibit GH syn and rel
GnRH




Gonadotropin
Source: Hypothalamus
Target: Gonadotropes
Action: Stimulate LH and FSH syn and rel
Oxytocin
Source: Posterior Pituitary pars Nervosa

Target: Pars Nervosa
Action: Stimulate Uterine contractions, milk ejection in female
ADH


Antidiuretic
Source: Posterior Pituitary Pars Nervosa

Target: Pars Nervosa
Action: Stimulate additional reabsorption of water, reduces urine production
Melatonin
Source: Pineal Gland
Target: Many
Action: Biorhythms and sleep cycles
PRL


Prolactin
Source: Pars Distalis Anterior Pituitary

Target: Breasts and gonads
Action: stimulate milk and gamete production
TSH


Thyroid Stimulating
Source: Pars Distalis Anterior Pituitary

Target: Thyroid Cells
Action: Stimulate production of T3 and T4
ACTH


Adrenocorticotropin
Source: Pars Distalis Anterior Pituitary

Target: Zonas fasciculata and reticularis of Adrenal Cortex
Action: Stimulate cortisol synt and rel
GH
Source: Pars Distalis Anterior Pituitary

Target: Somatic Cells and Hepatocytes
Action: Stimulate liver to secrete IGFs and direct action on bone and soft tissue growth
LH


Luteinizing
Source: Pars Distalis Anterior Pituitary

Target: Thecal Cells of Ovaries and Leydig of Testes
Action: Stimulate testosterone production and mass of the gonads
FSH


Follicle-Stimulating
Source: Pars Distalis Anterior Pituitary

Target: Granulosal cells of ovaries and Sertoli cells of Testes
Action: Stimulates aromatase enzyme activation in granulosal cells, nourish sperm in sertoli cells and stimulates Inhibin in both
Thymosin
Source: Thymus
Target: Immune system
Action: T-Cell function
T3 and T4
Source: Thyroid gland
Target: Most body cells
Action: regulate metabolic rate
Calcitonin
Source: Thyroid gland
Target: Bone
Action: increase calcium uptake by bone, decrease blood calcium
PTH

Parathyroid
Source: Parathyroid glands
Target: bone, gut, kidney
Action: increases blood calcium by increasing bone release. increases calcium absorption across gut to nephron
Aldosterone
Source: Adrenal Cortex   Z. glomerulosa
Target: Distal tubules of nephron
Action: stimulates reabsorption of sodium
Cortisol
Source: Z. Fasciculata of Adrenal Cortex
Target: Many body cells
Action: regulate body respone to stress
Androgens

Testosterone like steroids
Source: Z. Reticularis of Adrenal Cortex
Target: Many Body Cells
Action: Increase muscle mass and lipolysis
Epinephrine
Source: Adrenal Medulla

Action: sympathomimetic
Insulin
Source: beta cells of pancreas
Target: somatic cells of hepatocytes
Action: increase somatic cell uptake of glucose, promote protein, lipid, and glycogen synthesis
Glucagon
Source: alpha cells of pancreas
Target: somatic cells of hepatocytes
Action: decrease cell uptake of glucose, promote glycogen breakdown into glucose
Somatostatin
Source:  delta cells of Pancreas
Target: several
Action: regulate digestion, absorption of nutrients, regulate pancreas
Testosterone
Source: Leydig cells of Testis
Target: Somatic  cells
Action: anabolism, regulate productive functions, terminate bone growth
Inhibin
Source: Sertoli cells of Testes
Target: Pars Distalis
Action: Decrease FSH secretion
Estradiol
Source: Granulosa of Ovaries
Target: Somatic cells
Action: feminizing hormone
Inhibin
Source: Granulosa of Ovaries
Target: Pars distalis
Action: Decrease FSH
Progesterone/ Estradiol
Source: Corpus Luteum of Ovaries
Target: Reproductive System
Action: Promotes gestation
HCG

Human chorionic gonadotropin
Source: Placenta
Target: Corpus Luteum
Action: Maintains Corpus Luteum function
Lactotropes
synthesize prolactin
thyrotropes
synthesis thyrotropin
corticotropes
synthesize ACTH
Somatotropes
synthesize GH
Gonadotropes
Synthesize LH/FSH
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