Studydroid is shutting down on January 1st, 2019

by mtoom

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What tissues (5) does the α1 receptor act on?

  • Skin

  • Bladder

  • Gastrointestinal tract

  • Uterus

  • Eye

What tissues (2) does the α2 receptor act on?
  • Gastrointestinal tract
  • Pre-synaptic neurons
What tissues (3) does the β1 receptor act on?
  • Heart
  • Fat cells
  • Kidney
What tissues (6) does the β2 receptor act on?
  • Lungs
  • Muscles
  • Uterus
  • Gastrointestinal tract
  • Bladder
  • Liver
What receptor(s) cause constriction of blood vessels in skin?
What receptor(s) cause piloerection (i.e. smooth muscle contraction causing goosebumps)?
What receptor(s) cause constriction of body sphincters (in gastrointestinal tract and bladder)?
What receptor(s) cause contraction of uterus?
α1 and muscarinic
What receptor(s) cause contraction of radial muscle causing dilation of pupil (i.e. mydriasis)?
What is the general role of α1 receptors?
Constriction of smooth muscles
What receptor(s) cause relaxation of the gastrointestinal tract?
α2 and β2
What receptor(s) cause inhibition of pre-synaptic ganglionic neurons?
What is the general role of β1 receptors?
Increase cardiac performance and liberate energy
What receptor(s) increase heart rate and heart contractility?
What receptor(s) promote release of fat from cells?
What receptor(s) stimulate kidney to release renin causing an increase in blood volume?
What is the general role of β2 receptors?
Relax smooth muscle and liberate energy
What receptor(s) cause bronchodilation?
What receptor(s) cause vasodilation of blood vessels in muscle?
What receptor(s) relax the bladder?
What receptor(s) relax the uterus?
What receptor(s) cause glycogenolysis in liver, increasing blood sugar?
What receptor(s) cause bronchoconstriction?
What receptor(s) cause a decrease in contractility, rate and conduction of heart?
What receptor(s) cause relaxation of sphincters?
What receptor(s) cause contraction of circular muscle of eye (constricting pupil) and contraction of ciliary muscle of eye (causing near-vision focusing)?
What receptor(s) cause increasing of glandular secretions (i.e. lacrimal, salivary, bronchiall)?
What receptor(s) cause bladder to constrict?
What receptor(s) cause gastrointestinal tract to constrict?
What are the 5 effects of α1 receptor?
  • Constrict blood vessels in skin
  • Piloerection (smooth muscle contraction causing goosebumps)
  • Contraction of uterus
  • Contraction of radial muscle (causing pupil dilation)
  • Contraction of sphinters (gastrointestinal tract and bladder)
What are the 2 effects of α2 receptor?
  • Inhibit sympathetic autonomic ganglia (i.e. pre-synaptic ganglionic neurons)
  • Relax smooth muscle in gastrointestinal tract
What are 3 effects of β1 receptors?
  • Increase heart rate and contractility
  • Stimulate release of fat (i.e. lipolysis in adipocytes)
  • Stimulate kidney to release renin, increasing blood volume
What are 6 effects of β2 receptors?
  • Bronchodilation
  • Vasodilation of blood vessels in muscles
  • Relax uterus
  • Relax gastrointestinal tract
  • Relax bladder
  • Glycogenolysis in liver, increasing blood sugar
What are 8 effects of muscarinic receptors?
  • Bronchoconstriction (in lungs)
  • Reduced heart rate, contractility, conduction
  • Relax sphincters of gastrointestinal tract and bladder
  • Constrict bladder
  • Constrict gastrointestinal tract
  • Contract circular muscle of eye (pupil constriction, meiosis)
  • Contract ciliary muscle of eye (focus for near vision)
  • Increase glandular secretions (e.g. lacrimal, salivary, bronchial)
Describe relative effects of noradrenaline on alpha and beta adrenergic receptors.
A1 > B1, B2

(potent effect on A1)
Describe relative effects of adrenaline on alpha and beta adrenergic receptors.
B1, B2 > A1
Describe relative effects of isoproterenol on alpha and beta adrenergic receptors.
B1, B2 only
A1 zero
x of y cards