by ab1498

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Which of the amino acids have aliphatic side chains?
Gly, Ala, Val, Leu, Ile, Pro
Which of the amino acids have aromatic side chains?
Phe,Tyr, Trp
Which of the amino acids are basic?
His, Lys, Arg
Which of the amino acids are acidic?
Asp, Glu, Asn, Gln
Defects in the metabolism of which amino acid leads to maple syrup urine disease?
“Branched” amino acids (Val, Leu, Ile).
What disorders arise from defects in the metabolism of tyrosine?  Phenylalanine?
Tyr: Tyrosinosis, Albinism, Alcaptonuria Phe: Phenylketonuria (PKU)
Which amino acids have hydroxyl groups on the sidechain?  Which amino acids contain sulfur, When they are in proteins, what kinds of reactions do these amino acids occasionally undergo?
-OH: Ser, Thr -S: Cys, Met Reactions of -OH groups are phosphorylated Reactions of sulfhyroxyl groups oxidize to form dulsulfide linkages.
With respect to the amino acids that we discussed, what is the cause of pellagra?
A defect in the ability to for the body to metabolize tryptophan into niacin
Which amino acids are referred to as essential?
Phe, Val, Thr, Trp, Ile, Met, His, Arg, Leu, Lys   Mnemonic: “Pvt. Tim Hall”
Name 4 types of compounds for which amino acids are precursors
Glucose Neurotransmitters Hormone synthesis Porphyrins, purines, pyrimidines Building blocks for proteins (particularly enzymes)
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