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nontuberculous mycobacteria species - slowly growing species - 5
  • M. avium complex,
  • M. avium subsp paratuberculosis,
  • M. kansasii,
  • M. marinum,
  • M. xenopi 
M. avium complex is also know as
M. avium-intercellulari/intracellulari complex
m. avium - general characteristics - 1
slowly growing species
m. avium clinical infections
  • pulmonary problems
  • gastrointestinal problems
  • not a problem with other immunocompromised patients (cancer, ect.) 
m. avium, people more susceptible:
  • HIV patients - pulmonary problems
  • nonHIV patients - gastrointestinal problems
  • not a problem with other immunocompromised patients (cancer, ect.) 
m. avium mode of transmission
transmission unknown or mode of illness unknown
m. avium lab diagnosis - microscopic id:
looks like long rods with beading,
beads not always seen with staining
m. avium subsp paratuberculosis - clinical infections/manifestations - 2
Crohn's disease
gastrointestinal
m. kansasii - type of pathogen
pulmonary pathogen
m. kansasii - what type of chromogen and characteristics
photochromogen,
betacarotene - orange,
as culture ages it turns to red,
m. kansasii - culture characteristics - 4
  • grows 24C
  • optimum 37C
  • no growth 42C 
  • slowly growing species
m. marinum - clinical infections/manifestations
not pulmonary
t-cell susppression
m. marinum - general characteristics - 4
water
cold loving
photochromogen
slowly growing species
m. xenopi - clinical infections/manifestations - 3
spinal infections
arthroscopic laminectomies (contaminated tapwater)
hospital showers (nosocomial)
m. xenopi - culture characteristics
thermophilic 42C - 50C
slowly growing species
nontuberculous mycobacteria species - 
rapidly growing species - 2
m. fortuitum group
m. leprae
m. fortuitum - general characteristics
nonchromogen,
rapidly growing species
m. fortuitum - clinical infections/manifestations
pulmonary disease
requires a severe underlying problem
m. fortuitum - transmission
example - dialysis patients, hemodialysis filters contaminated
m. fortuitum - treatment
resistent to the antimycobacterial drugs,
routine antibiotics work
m. leprae also known as
Hansen's disease
m. leprae - culture characteristics
rapidly growing species,
will not gow on artificial media
can grow on the pads of mouse's feet (bottom)
m. leprae - transmission
unknown
m. leprae - what species can contract it
only humans and armadillos
m. leprae - 2 forms of disease and name
tuberculoid and lepromatous
m. leprae - tuberculoid form - characteristics
milder
good response (by cell mediated immunity)
m. leprae - lepromatous form - characteristics
more severe
poor response (by cell mediated immunity)
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